Pituitary Adenylate Cyclase-Activating Polypeptide

A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS and VASOACTIVE INTESTINAL PEPTIDE RECEPTOR. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.

Also Known As:

PACAP; PACAP-27; PACAP-38; PACAP27; PACAP38; Pituitary Adenylate Cyclase Activating Polypeptide; Pituitary Adenylate Cyclase Activating Polypeptide 27; Pituitary Adenylate Cyclase Activating Polypeptide 38

Pharmalogical Action Categories:

Growth Substances
Neurotransmitter Agents
Vasodilator Agents

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Nerve Growth Factors: 5170
      - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138
  - Nerve Tissue Proteins: 3
    - Neuropeptides: 6903
      - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138
    - Nerve Growth Factors: 5170
      - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Nerve Growth Factors: 5170
      - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138
  - Neuropeptides: 6903
    - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Nerve Growth Factors: 5170
    - Pituitary Adenylate Cyclase-Activating Polypeptide: 1138

Andras Büki Selected Research

Andras Büki Research Topics

Disease

Drug/Important Bio-Agent (IBA)